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강혁Hyuk Kang

  • 소속 화학과
  • 연구실원천관 214
  • 이메일 hkang@ajou.ac.kr
  • 내선번호2598

관심분야

  • 생체분자에 대한 질량/형태 선택적 레이저 분광학

학력

  • 2002.08 서울대학교 박사

경력

    Postdoc,  2005 - 2007, Pacific Northwest National Laboratory
Postdoc,  2003 - 2004, Laboratoire de Photophysique Moléculaire du CNRS 
                         (Laboratory of Molecular Photophysics of the CNRS)

연구분야

    Photophysics of biomolecular building blocks
Conformer-specific UV/IR spectroscopy of biological building blocks and bioactive molecules
Conformational isomerization of biomolecules
Analytical application of cryogenic ion spectroscopy

대표논문

  • [논문] 권장한, 송경옥, 이민지, Kazuya Tsuruta, Masaaki Fujii, Shun-ichi Ishiuchi, 강혁, Cryogenic Ion Spectroscopy of a Singly Protonated Peptide DYYVVR: Locating Phosphorylation Sites of a Kinase Domain, JOURNAL OF PHYSICAL CHEMISTRY LETTERS, pp. 7103-7108 (8월, 2020)
  • [논문] 손운용, 김정진, 전명원, Masaaki Fujii, Shun-Ichi Ishiuchi, Takuma Aoki, 강혁, Entropic Effect Makes a More Tightly Folded Conformer of a β-Amino Acid Less Stable: UV-UV Hole Burning and IR Dip Spectroscopy of L-β3-Homotryptophan by Laser Desorption Supersonic Jet Technique, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, Vol.20, No.30, pp. 19979-19986 (7월, 2018)
  • [논문] Patrick S. Walsh, 강혁, Carl McBurney, Jacob C. Dean, Samuel H. Gellman, Timothy S. Zwier, Conformation-specific spectroscopy of capped Glutamine-containing peptides: Role of a single glutamine residue on peptide backbone preferences, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, Vol.18, No.16, pp. 11306-11322 (3월, 2016)
  • [논문] 강혁, Claude Dedonder-Lardeux, G?raldine F?raud, Christophe Jouvet, New Method for Double-Resonance Spectroscopy in a Cold Quadrupole Ion Trap and Its Application to UV?UV Hole-Burning Spectroscopy of Protonated Adenine Dimer, JOURNAL OF PHYSICAL CHEMISTRY LETTERS, Vol.5, No.15, pp. 2760-2764 (7월, 2014)
  • [논문] 손운용, 김민호, 김상수, 박영동, 강혁, Solvent-assisted conformational isomerization and the conformationally-pure REMPI spectrum of 3-aminophenol, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, Vol.13, No.15, pp. 7037-7042 (4월, 2011)

연구활동

  • [논문] 전효남, 권장한, 강혁, Ultraviolet photodissociation spectra of singlyprotonated hexapeptides DYYVVR, DYFVVR, and DFYVVRat room temperature, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, pp. 777-779 (9월, 2023)
  • [논문] 안희준, NKENKU ANIMBOM BUMA CARL, 유영동, 강혁, 김유권, Understanding the pulsed laser-induced modificationprocesses of TiO2 nanomaterials in aqueous solution, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, pp. 1-11 (4월, 2023)
  • [논문] Vinayak Juvekar, 이효원, 조명기, 강혁, 이동준, 송주만, 김환명, 제종태, A red-emissive two-photon fluorescent probe for mitochondrial sodium ions in live tissue, CHEMICAL COMMUNICATIONS, pp. 8929-8932 (8월, 2021)
  • [논문] Vinayak Juvekar, 임창수, 강혁, 노충균, 송득화, 이동준, 김환명, 신성재, Near-Infrared Ratiometric Two-Photon Probe for pH Measurement in Human Stomach Cancer Tissue, ACS APPLIED BIO MATERIALS, pp. 2135-2141 (3월, 2021)
  • [논문] Vinayak Juvekar, 임창수, 강혁, 박상준, 송경옥, 이동준, 김환명, An azo dye for photodynamic therapy that is activated selectively by two-photon excitation, CHEMICAL SCIENCE, pp. 1-8 (1월, 2021)
  • [논문] 권장한, 송경옥, 이민지, Kazuya Tsuruta, Masaaki Fujii, Shun-ichi Ishiuchi, 강혁, Cryogenic Ion Spectroscopy of a Singly Protonated Peptide DYYVVR: Locating Phosphorylation Sites of a Kinase Domain, JOURNAL OF PHYSICAL CHEMISTRY LETTERS, pp. 7103-7108 (8월, 2020)
  • [논문] 박상준, Yen Leng Pak, 강혁, 송경옥, 임유빈, 김환명, Jean Bouffard, 윤주영, Endoplasmic Reticulum-Targeted Ratiometric N-Heterocyclic Carbene Borane Probe for Two-Photon Microscopic Imaging of Hypochlorous Acid, ANALYTICAL CHEMISTRY, Vol.90, No.21, pp. 12937-12943 (11월, 2018)
  • [논문] 손운용, 김정진, 전명원, Masaaki Fujii, Shun-Ichi Ishiuchi, Takuma Aoki, 강혁, Entropic Effect Makes a More Tightly Folded Conformer of a β-Amino Acid Less Stable: UV-UV Hole Burning and IR Dip Spectroscopy of L-β3-Homotryptophan by Laser Desorption Supersonic Jet Technique, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, Vol.20, No.30, pp. 19979-19986 (7월, 2018)
  • [논문] Mai Hoang Tran, 서은정, 강혁, Alka Mansukhani, Quynh-Anh T. Nguyen, 민수홍, 이욱진, 주일로, 최주영, 홍순선, 이상윤, NEDD4-induced degradative ubiquitination of phosphatidylinositol 4-phosphate 5-kinase a and its implication in breast cancer cell proliferation, JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, Vol.22, No.9, pp. 4117-4129 (5월, 2018)
  • [논문] 이상윤, 강혁, Nonresonant Contribution in Pump?Probe Transient Ion Signal of Adenine, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, Vol.39, No.3, pp. 408-410 (2월, 2018)
  • [논문] 김유권, 김유나, 이규성, 강혁, Enhanced photoactivity of stable colloidal TiO2 nanoparticles prepared in water by nanosecond infrared laser pulses, KOREAN JOURNAL OF CHEMICAL ENGINEERING, Vol.34, No.6, pp. 1822-1826 (4월, 2017)
  • [논문] 허철호, Avik Ranjan Sarkar, 강혁, 김정진, 정태성, 백성훈, 김환명, 묵인희, A quadrupolar two-photon fluorescent probe for in vivo imaging of amyloid-b plaques, CHEMICAL SCIENCE, pp. 1-7 (4월, 2016)
  • [논문] Patrick S. Walsh, 강혁, Carl McBurney, Jacob C. Dean, Samuel H. Gellman, Timothy S. Zwier, Conformation-specific spectroscopy of capped Glutamine-containing peptides: Role of a single glutamine residue on peptide backbone preferences, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, Vol.18, No.16, pp. 11306-11322 (3월, 2016)
  • [논문] 정해준, 김정진, 강혁, Laser Desorption of Tryptophan from Tryptophan?HCl Salt on a Graphite Substrate, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, Vol.37, No.3, pp. 394-396 (3월, 2016)
  • [논문] 이소영, 강혁, Quantum Mechanical Study on Hydrogen Bonds between 3-Aminophenol and CHxCl4???x (x?=?1, 2, 3): Effect of the Number of Halogen Atoms#, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, Vol.36, No.3, pp. 752-756 (3월, 2015)
  • [논문] 이소영, 강혁, Quantum Mechanical Study on the Blue-Shifting Hydrogen-Bond between 3-Aminophenol and CHX3 (X = F, Cl), BULLETIN OF THE KOREAN CHEMICAL SOCIETY, Vol.36, No.1, pp. 111-116 (1월, 2015)
  • [논문] Avik Ranjan Sarkar, 허철호, Hardev Singh Virdi, 강혁, 김정진, 이효원, 김은진, 김환명, 강철훈, A cysteamine-selective two-photon fluorescent probe for ratiometric bioimaging, CHEMICAL COMMUNICATIONS, pp. A-D (12월, 2014)
  • [논문] 강혁, Claude Dedonder-Lardeux, G?raldine F?raud, Christophe Jouvet, New Method for Double-Resonance Spectroscopy in a Cold Quadrupole Ion Trap and Its Application to UV?UV Hole-Burning Spectroscopy of Protonated Adenine Dimer, JOURNAL OF PHYSICAL CHEMISTRY LETTERS, Vol.5, No.15, pp. 2760-2764 (7월, 2014)
  • [논문] Mitsuhiko Miyazaki, 강혁, 송재규, 최창민, 한노수, Masaaki Fujii, 김남준, MODE-specific deactivation of adenine at the singlet excited states, JOURNAL OF CHEMICAL PHYSICS, Vol.139, No.12, pp. 124311-124311 (9월, 2013)
  • [논문] 손운용, 강정석, 이소영, 강혁, Fluorescence excitation spectrum and solvent-assisted conformational isomerization (SACI) of jet-cooled acetaminophen, CHEMICAL PHYSICS LETTERS, Vol.581, pp. 36-41 (8월, 2013)
  • [논문] 정해준, 김환명, 허철호, Masaaki Fujii, Shun-ichi Ishiuchi, 손운용, 강혁, Gas-Phase Spectroscopy of Laser-Desorbed Acedan and Proline-Acedan, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, Vol.34, No.8, pp. 2241-2242 (8월, 2013)
  • [논문] 손운용, 강정석, 이소영, Mitsuhiko Miyazaki, Shun-ichi Ishiuchi, 민아름, 최명룡, 강혁, Masaaki Fujii, Conformationally resolved spectra of Acetaminophen by UV-UV hole burning and IR dip spectroscopy in gas phase, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, Vol.15, No.3, pp. 957-964 (1월, 2013)
  • [논문] 손운용, 강성식, 박영동, 이소영, 조근진, 강혁, Solvent-Assisted Conformational Isomerization (SACI) of meta-Substituted Phenols: Tuning Relative Stability, Isomerization Barrier, and IVR Rate, CHEMICAL PHYSICS LETTERS, Vol.525, pp. 37-43 (2월, 2012)
  • [논문] 김남준, 강혁, 김형민, 안태규, 장진영, 허지영, 김성근, Femtosecond decay dynamics of intact adenine and thymine base pairs in supersonic jet, ChemPhysChem, Vol.12, No.10, pp. 1935-1939 (7월, 2011)
  • [논문] 손운용, 김민호, 김상수, 박영동, 강혁, Solvent-assisted conformational isomerization and the conformationally-pure REMPI spectrum of 3-aminophenol, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, Vol.13, No.15, pp. 7037-7042 (4월, 2011)
  • [논문] Ivan Alata, 김민호, 김상수, 손운용, Alexander Patzer, Claude Dedonder-Lardeux, Markus Sch?tz, Michel Broquier, 강혁, Christophe Jouvet, Otto Dopfer, Microhydration effects on the electronic spectra of protonated polycyclic aromatic hydrocarbons: [naphthalene-(H2O)n = 1,2]H+, JOURNAL OF CHEMICAL PHYSICS, Vol.134, No.7, pp. 074037-1-074307-7 (2월, 2011)
  • [논문] 손운용, 김민호, 김상수, 강혁, Computational study of 3-aminophenol?(CO2)1 cluster: CO2 capture ability of 3-aminophenol, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, Vol.263, No.10, pp. 2806-2808 (10월, 2010)
  • [논문] 김남준, 김성근, 안태규, 이상학, 장진영, 강혁, Excited state lifetime of adenine near the first electronic band origin, JOURNAL OF CHEMICAL PHYSICS, Vol.133, pp. 154311-1-154311-4 (10월, 2010)
  • [논문] 김민호, 김상수, 박영동, 강혁, REMPI and IR-UV double resonance spectroscopy of 3-aminophenol?(NH3)1 cluster in the gas phase, JOURNAL OF MOLECULAR SPECTROSCOPY, Vol.263, No.1, pp. 51-55 (9월, 2010)
  • [논문] 호쑨흥, 강혁, 모선일, 장혜영, Electro-Organocatalysis: Enantioselective a-alkylation of aldehydes, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, pp. 4436-4441 (7월, 2010)
  • [논문] 강혁, 김민호, 김상수, Effects of Amino Substitution on the Excited State Hydrogen Transfer in Phenol: A TDDFT Study, Bulletin of the Korean Chemical Society, Vol.30, No.7, pp. 1481-1484 (7월, 2009)
  • [논문] Arzu Umar, 강혁, Annemieke M. Timmerm, John A. Foekens, John W. M. Martens, Ljiljana Pasa-Tolic, Marion E. Meijer-van, Maxime P. Look, Michael A. den Bakke, Navdeep Jaitly, Theo M. Luider, Identification of a Putative Protein Profile Associated with Tamoxifen Therapy Resistance in Breast Cancer, Molecular & Cellular Proteomics, Vol.8, No.6, pp. 1278-1294 (6월, 2009)
  • [논문] 강혁, Transient Photoelectron Spectrum of NaI During Photodissociation at 307 nm, Bulletin of the Korean Chemical Society, Vol.30, No.4, pp. 775-776 (4월, 2009)
  • [논문] 오한빈, 강혁, 박수진, 안화근, 이범구, 이선영, 이예원, 조기호, Electron Capture Dissociation of Proteins Initiated by Photoelectrons Generated from 266 nm UV Laser Radiation on an ICR Cell Wall, Bulletin of the Korean Chemical Society, Vol.29, No.9, pp. 1673-1677 (9월, 2008)
  • [논문] Richard D. Smith, 강혁, Aleksey V. Tolmachev, Errol W. Robinson, Ljiljana Paša-T, Natacha M. Lourette, Si Wu, Trapped-Ion Cell with Improved DC Potential Harmonicity for FT-ICR MS, Journal of the American Society for Mass Spectrometry, Vol.19, No.4, pp. 586-597 (4월, 2008)
해당 데이터는 존재하지 않습니다.
  • [학술회의] 강혁, Spectroscopy of Consecutive Tyrosine Residues: Singly Protonated DYYVVR, Asia-Oceania Mass Spectrometry Conference, (8월, 2023)
  • [학술회의] 권장한, 강혁, 송경옥, 이민지, Kazuya Tsuruta, Shun-ichi Ishiuchi, Cryogenic Ion Spectroscopy of Singly Protonated Peptide DYYVVR for Identifying Phosphorylation Sites , The 6th Asian Workshop on Molecular Spectroscopy, (11월, 2022)
  • [학술회의] 강혁, Cryogenic Ion Spectroscopy of DYYVVR: Locating the Phosphorylation Site of a Janus Homology Domain, The 23rd East Asian Workshop on Chemical Dynamics, (9월, 2019)
  • [학술회의] 김유권, 강혁, Stable colloidal suspension of TiO2 nanoparticles in aqueous solution prepared by nanosecond laser pulses and their photocatalytic performances, 5th International Conference on Advanced Nanoparticle Generation and Excitation by Lasers in Liquids (ANGEL), pp. P-II-4- (6월, 2018)
  • [학술회의] 강혁, Non-Radiative Deactivation of Biological Building Blocks, The 21st East Asian Workshop on Chemical Dynamics, (12월, 2017)
  • [학술회의] 강혁, Novel double-resonance laser spectroscopy technique in a cold quadrupole ion trap and its application to protonated adenine dimer, Pacifichem2015, (12월, 2015)
  • [학술회의] 강혁, Double Resonance Spectroscopy of Protonated Adenine Dimer in a Cold Quadrupole Ion trap, 19th East Asian Workshop on Chemical Dynamics, (10월, 2015)
  • [학술회의] 강혁, New UV-UV Hole Burning Spectroscopy Method in a Quadrupole Ion Trap and Its Application to Protonated Adenine Dimer, IUPAC 2015, (8월, 2015)
  • [학술회의] 강혁, UV-UV HOLE-BURNING SPECTROSCOPY OF A PROTONATED ADENINE DIMER IN A COLD QUADRUPOLE ION TRAP, International Symposium on Molecular Spectroscopy, (6월, 2015)
  • [학술회의] 강혁, Solvent-Assisted Conformational Isomerization of Substituted Phenols and a New Method for Double Resonance Spectroscopy in a Quadrupole Ion Trap, Shining Light on Molecular Structure, (9월, 2014)
  • [학술회의] 강혁, REMPI and Double Resonance Spectroscopy of L-β-Homotryptophan in Gas Phase, IBBI 14 - Conference on Isolated Biomolecules and Biomolecular Interactions, (5월, 2014)
  • [학술회의] 강혁, Conformer-Specific Spectroscopy and Conformational Isomerization of Bio-Active Molecules, The 15th Asian Chemical Congress, (8월, 2013)
  • [학술회의] 강혁, Solvent-Assisted Conformational Isomerization of Acetamophen in the Gas Phase, Biological molecules in the gas phase and in solution, (7월, 2013)
  • [학술회의] 강혁, Solvent-Assisted Conformational Isomerization (SACI) of meta-Substituted Phenols: Tuning Relative Stability, Isomerization Barrier, and IVR Rate, The 16th East Asian Workshop on Chemical Dynamics, (4월, 2012)
  • [학술회의] 강혁, Solvent-Assisted Conformational Isomerization of Drugs and Neurotransmitters in the Gas Phase, Isolated Biomolecules and Biomolecular Interactions 2012, (1월, 2012)
  • [학술회의] 강혁, Solvent-Assisted Conformational Isomerization (SACI) of meta-Substituted Phenols, 15th East Asian Workshop on Chemical Dynamics, (5월, 2011)
  • [학술회의] 강혁, REMPI and IR-UV double resonance spectroscopy of 3-aminophenol-ammonia cluster, Pacifichem2010, (12월, 2010)
  • [학술회의] 강혁, Solvent-assisted conformational ionization of 3-aminophenol, Molecular and ionic clusters conference, (9월, 2010)
  • [학술회의] 강혁, REMPI and IR-UIV double resonance spectroscopy of 3-aminophenol-ammonia cluster, The 14th Ease Asian Workshop on Chemical Dynamics, pp. 17-18 (5월, 2010)
  • [학술회의] 강혁, REMPI and IR-UV double resonance spectroscopy of aminophenol-ammonia clusters, Mini International Symposium on Molecular Science for Supra Functional Systems, pp. 7-8 (1월, 2010)
  • [학술회의] 강혁, Christophe Jouvet, Gilles Gregoire, Ultrafast laser-induced dissociation of protonated tryptophan-leucine dipeptide, Korean-French Symposium on Chemical Dynamics, Vol.3, No.1, pp. 24-24 (7월, 2008)
  • [학술회의] 강혁, C. Jouvet, G. Gregoire, Excited State Hydrogen Transfer in Protonated Amino Acids: An Ultrafast Non-Radiative Decay Pathway of Biological Molecules, Asian Conference on Ultrafast Phenomena, Vol.5, No.1, pp. 22-23 (1월, 2008)
  • [학술회의] 권장한, 강혁, 전효남, UV photodissociation spectroscopy of protonated tyrosine at room temperature with a new QIT-TOF mass spectrometer, 대한화학회 제 130회 학술발표회, (10월, 2022)
  • [학술회의] 권장한, 강혁, 송경옥, 전효남, Locating the Phosphorylation Site of a Janus Homology Domain by Cryogenic Ion Spectroscopy of Singly Protonated DYYVVR, 제134차 대한화학회 물리화학분과 여름 심포지엄, (7월, 2021)
  • [학술회의] 전효남, 강혁, 권장한, Cryogenic Ion Spectroscopy of DYYVVR: Structural Assignment by IR Spectroscopy, 대한화학회 제127회 학술발표회, (4월, 2021)
  • [학술회의] 송경옥, 강혁, 권장한, Cryogenic Ion Spectroscopy of DYYVVR: Structural Assignment by DFT Calculation, 대한화학회 제127회 학술발표회, (4월, 2021)
  • [학술회의] 공다인, 강혁, 김유권, Effect of Pulsed Laser Fluence on the Morphology of MoS2 Nanoparticles, 대한화학회 제127회 학술발표회, (4월, 2021)
  • [학술회의] 권장한, 강혁, Construction of a New Quadrupole Ion Trap – Time of Flight Mass Spectrometer for Spectroscopy of Biomolecular Ions, 대한화학회 제125회 학술발표회, (7월, 2020)
  • [학술회의] 공다인, 강혁, 김유권, Pulsed laser-induced surface modification of TiO2 nanoparticles , 대한화학회 제125회 학술발표회, (7월, 2020)
  • [학술회의] 안희준, 강혁, 김유권, 유영동, Observation of changes in the morphology and bulk phases of TiO2 nanoparticles under pulsed laser irradiation in water, 대한화학회 제123회 학술발표회, (4월, 2019)
  • [학술회의] 김다연, 김유권, 강혁, 김정진, Environment-friendly synthesis of TiO2 nanoparticles in aqueous solution with a nanosecond infrared laser, 제117회 대한화학회 춘계학술대회, pp. 562-562 (4월, 2016)
  • [학술회의] 강혁, Solvent-Assisted Conformational Isomerization (SACI) of Bio-active Molecules, 112차 대한화학회 물리화학분과회 심포지엄, (3월, 2013)
  • [학술회의] 강혁, Targeted Tandem Mass Spectrometry for High-Throughput Comparative Proteomics employing nano-LC coupled with FTICR MS, 대한화학회 제102회 총회 및 학술발표회, Vol.102, No.2, pp. 862-862 (10월, 2008)
  • [학술회의] 강혁, An alternative approach to shot-gun proteomics: targeted MS/MS for high-throughput comparative proteomics and potential biomarker discovery, 한국질량분석학회 2008 여름정기학술대회, Vol.2008, No.1, pp. 47-47 (8월, 2008)
  • [학술회의] 강혁, Christophe Jouvet`, Gilles Gregoire, Ergodic vs. non-ergodic pathways during laser-induced dissociation of protonated tryptophan-leucine dipeptide, 대한화학회 제101회 총회 및 학술발표회, Vol.101, No.1, pp. 259-259 (4월, 2008)
  • [학술회의] 강혁, Excited State Hydrogen Transfer in Protonated Amino Acids: An Ultrafast Non-Radiative Decay Pathway of Biological Molecules, 2007년 제3차 대한화학회 물리분과회, Vol.0, No.0, pp. 2-2 (9월, 2007)
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