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대학약학대학약학과

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김홍표Hong Pyo Kim

  • 소속 약학과
  • 연구실약학관309호
  • 이메일 ghim@ajou.ac.kr
  • 내선번호3452

관심분야

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학력

  • 1998.02 서울대학교대학원 박사

경력

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대표논문

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연구활동

  • [논문] 김성열, 송재형, 김홍표, 장선영, 김길남, 안재희, 양윤미, 정명선, 정재헌, 조재원, 차영길, 고현정, Obesity Exacerbates Coxsackievirus Infection via Lipid-Induced Mitochondrial Reactive Oxygen Species Generation, Immune Network, Vol.22, No.2, pp. e19-e39 (4월, 2022)
  • [논문] 유희민, 이필준, 조남기, 김홍표, Active Turnover of Heme in Hibernation Period in Mammals, FRONTIERS IN PHYSIOLOGY, pp. fphys.2019.01586 -fphys.2019.01586 (1월, 2020)
  • [논문] 류지연, 김진현, 원은정, 이한아름, 휴이엠마뉴엘, 김홍표, 윤태종, Ultrasound-activated particles as CRISPR/Cas9 delivery system for androgenic alopecia therapy, BIOMATERIALS, pp. 1-11 (12월, 2019)
  • [논문] 우승제, 이필준, 유희민, 조남기, 김홍표, Differential Mechanism of ATP Production Occurs in Response to Succinylacetone in Colon Cancer Cells, MOLECULES, pp. E355-E355 (10월, 2019)
  • [논문] 김정민, 안성진, 김홍표, 신일진, 공준표, 안성찬, 이주창, 정다람, 표정주, 황석영, 김형수, 노민수, 2-Phenyl-8-(1-phenylallyl)-chromenone compounds have a pan-PPAR modulator pharmacophore, BIOORGANIC & MEDICINAL CHEMISTRY, Vol.27, No.13, pp. 2948-2958 (7월, 2019)
  • [논문] 정혜경, 김홍표, 이동주, 백승훈, Structure analysis and antioxidant activities of an amylopectin-typepolysaccharide isolated from dried fruits of Terminalia chebula, CARBOHYDRATE POLYMERS, pp. 100-108 (5월, 2019)
  • [논문] 류지연, 조은이, 박상규, 이한아름, 홍신희, 박혜선, 홍관수, 김홍표, 윤태종, Lechitin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes, Journal of Nanobiotechnology, pp. 19-31 (1월, 2019)
  • [논문] 김홍표, 유희선, 김형수, 이동주, 김석호, DDQ-Promoted Mild and Efficient Metal-Free Oxidative α-Cyanation of N-Acyl/Sulfonyl 1,2,3,4-Tetrahydroisoquinolines, MOLECULES, Vol.23, No.12, pp. 3223-3235 (12월, 2018)
  • [논문] 이필준, 박혜진, 김홍표, 조남기, Aquaporin 11-Dependent Inhibition of Proliferation by Deuterium Oxide in Activated Hepatic Stellate Cells., Molecules, Vol.12, No.12, pp. 3209-3218 (12월, 2018)
  • [논문] 박혜진, 이필준, 김홍표, 조남기, 3,5-Diethoxy-3'-Hydroxyresveratrol (DEHR) Ameliorates Liver Fibrosis via Caveolin-1 Activation in Hepatic Stellate Cells and in a Mouse Model of Bile Duct Ligation Injury, MOLECULES, Vol.11, pp. 2833-2841 (10월, 2018)
  • [논문] 박재우, 김형수, 김홍표, 이필준, 강병헌, 김병삼, 김종헌, 정수월, 정헌택, 조성찬, 최우균, 백승훈, The novel resveratrol derivative 3,5-diethoxy-3',4'-dihydroxy-trans-stilbene induces mitochondrial ROS-mediated ER stress and cell death in human hepatoma cells in vitro., ACTA PHARMACOLOGICA SINICA, Vol.38, No.11, pp. 1486-1500 (11월, 2017)
  • [논문] 김정화, 김홍표, Kim HW, Park SW, 김태범, 성상현, Hepatoprotective Flavonoids in Opuntia ficus-indica Fruits by Reducing Oxidative Stress in Primary Rat Hepatocytes., PHARMACOGNOSY MAGAZINE, Vol.13, No.51, pp. 472-476 (7월, 2017)
  • [논문] 김정화, 김홍표, 성상현, Cytotoxic pterosins from Pteris multifida roots against HCT116 human colon cancer cells., BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Vol.27, No.14, pp. 3144-3147 (7월, 2017)
  • [논문] 김홍표, 김정화, 김현우, 양희정, 성상현, Lignans from Opuntia ficus-indica seeds protect rat primary hepatocytes and HepG2 cells against ethanol-induced oxidative stress., BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, Vol.81, No.1, pp. 181-183 (1월, 2017)
  • [논문] 우승제, 이필준, 성상현, 지준구, 김홍표, Bisdemethoxycurcumin Induces Apoptosis in Activated Hepatic Stellate Cells via Cannabinoid Receptor 2, MOLECULES, Vol.20, No.1, pp. 1277-1292 (1월, 2015)
  • [논문] 조남기, 김홍표, 김영중, 김현우, 이종환, 이희경, 전병주, 성상현, The effects of Betula platyphylla bark on amyloid beta-induced learning and memory impairment in mice, FOOD AND CHEMICAL TOXICOLOGY, Vol.74C, pp. 156-163 (12월, 2014)
  • [논문] 정종혜, 김정화, 김혜령, 박정일, 성상현, 양민혜, 양희정, 유헌승, 홍민지, 김홍표, 김진웅, Stereoisomer-specific anti-cancer activities of ginsenoside Rg3 and Rh2 in hepG2 cells: disparity in cytotoxicity and autophagy-inducing effects by their 20(S)-epimers, BIOLOGICAL & PHARMACEUTICAL BULLETIN, Vol.37, No.12, pp. 11-17 (12월, 2014)
  • [논문] 신일진, 이필준, 김형수, 서승룡, 김홍표, Upregulation of both heme oxygenase-1 and ATPase inhibitory factor 1 renders tumoricidal activity by synthetic flavonoids via depleting cellular ATP, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Vol.24, No.20, pp. 4845-4849 (10월, 2014)
  • [논문] Ryter SW, Choi AMK, 김홍표, Profibrogenic phenotype in caveolin-1 deficiency via differential regulation of STAT-1/3 proteins, BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE, Vol.92, No.5, pp. 370-378 (10월, 2014)
  • [논문] 김홍표, Lightening up Light Therapy: Activation of Retrograde Signaling Pathway by Photobiomodulation, BIOMOLECULES & THERAPEUTICS, Vol.22, No.6, pp. 491-496 (9월, 2014)
  • [논문] 김홍표, Ryter, Stefan, 정헌택, Heme Oxygenase-1 as a Novel Metabolic Player, OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, Vol.2013, pp. 814058-1-814058-2 (12월, 2013)
  • [논문] Lam, Hilaire, 김홍표, An CH, Bhashyam, AR, Biswal SS, Cervo M, Cloonan, SM, Franks JM, Haley KJ, Haspel, JA, Mahmood A, Mizumura K, Owen CA, Quackenbush J, Rahman I, Ryter, Stefan, Sathirapongsasuti JF, Shan B, Silverman EK, Singh A, Tesfaigzi Y, Washko GR, Yao H, Choi, Augustine MK, Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction, JOURNAL OF CLINICAL INVESTIGATION, Vol.123, No.12, pp. 5212-5230 (12월, 2013)
  • [논문] 조남기, 김홍표, 김현우, 양희정, 이미나, 허정무, 성상현, Neuroprotective Benzyl Benzoate Glycosides from Disporum viridescens Roots in HT22 Hippocampal Neuronal Cells., JOURNAL OF NATURAL PRODUCTS, Vol.76, No.12, pp. 2291-2297 (11월, 2013)
  • [논문] 이선진, Choi, Augustine MK, Zhang, JL, 김홍표, Mitochondrial dysfunction induces formation of lipid droplets as a generalized response to stress., OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, Vol.2013, pp. 327167-1-327168-10 (9월, 2013)
  • [논문] Lee M, 김홍표, Kang J, Lee SH, Yang H, 김영중, 정은주, 성성현, Salicortin-Derivatives from Salix pseudo-lasiogyne Twigs Inhibit Adipogenesis in 3T3-L1 Cells via Modulation of C/EBPα and SREBP1c Dependent Pathway, MOLECULES, Vol.18, No.9, pp. 10484-10496 (8월, 2013)
  • [논문] 조남기, 김홍표, Choi JH, 양희정, 이기용, 정은주, 허정무, 성상현, Cognitive-enhancing effects of Rhus verniciflua bark extract and its active flavonoids with neuroprotective and anti-inflammatory activities., FOOD AND CHEMICAL TOXICOLOGY, Vol.58, pp. 355-361 (8월, 2013)
  • [논문] 이기용, 김홍표, 김승현, 김태범, 전병준, 정은주, 조남기, 허정무, 성상현, Cognition-enhancing and neuroprotective activities of the standardized extract of Betula platyphylla bark and its major diarylheptanoids., PHYTOMEDICINE, pp. 1315-1320 (11월, 2012)
  • [논문] 양혜경, 이필준, 정은주, 김홍표, 김영중, Selective apoptosis in hepatic stellate cells mediates the antifibrotic effect of phenanthrenes from Dendrobium nobile., PHYTOTHERAPY RESEARCH, pp. 974-980 (7월, 2012)
  • [논문] 장밍, 김홍표, 김슬기, 백승훈, 이그나로, 조연수, 조홍래, 정헌택, Sensing endoplasmic reticulum stress by protein kinase RNA-like endoplasmic reticulum kinase promotes adaptive mitochondrial DNA biogenesis and cell survival via heme oxygenase-1/carbon monoxide activity., FASEB JOURNAL, pp. 2558-2568 (6월, 2012)
  • [논문] 다나카, 김홍표, 라이터, 스톨즈, 이선진, 장멍, 진양, 최명근, Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death, AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, pp. 507-514 (4월, 2012)
  • [논문] 정수월, 김홍표, 강영호, 권민영, 이선진, 정헌택, 마크 페렐라, Transforming growth factor-β1 suppression of endotoxin-induced heme oxygenase-1 in macrophages involves activation of Smad2 and downregulation of Ets-2., JOURNAL OF CELLULAR PHYSIOLOGY, pp. 351-360 (1월, 2012)
  • [논문] Lee SJ, Ryter SW, 김홍표, Jin-Fu Xu, Nakahira K, 김영삼, Choi AMK, Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation, AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, Vol.45, No.4, pp. 867-873 (10월, 2011)
  • [논문] Lee SJ, 김홍표, Jin Y, Choi AMK, Ryter SW, Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis, AUTOPHAGY, Vol.7, No.8, pp. 829-839 (8월, 2011)
  • [논문] Wang X, 김홍표, Choi AMK, Lee SJ, Wang Y, Ryter SW, Carbon monoxide inhibits Fas activating antibody-induced apoptosis in endothelial cells, MEDICAL GAS RESEARCH, pp. 1-11 (5월, 2011)
  • [논문] Lee SJ, 김홍표, Alastalo TP, Chen ZH, Feghali-Bostwick C, Guo L, Ifedigbo E, Jin Y, Li M, Liu X, Rabinovitch M, Ryter SW, Sawada H, Smith A, Choi AMK, Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol.183, No.3, pp. 649-658 (3월, 2011)
  • [논문] Nakahira K, 김홍표, Cernadas M, Dolinay T, Englert JA, Fitzgerald KA, Haspel JA, Lam HC, Lee SJ, Rabinovitch M, Rathinam VA, Ryter SW, Choi AMK, Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome, NATURE IMMUNOLOGY, Vol.12, No.3, pp. 222-230 (3월, 2011)
  • [논문] 김홍표, Son Y, 배현옥, 백승훈, 우제문, 정수월, 정헌택, Heme oxygenase-1 comes back to endoplasmic reticulum, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol.404, No.1, pp. 1-5 (1월, 2011)
  • [논문] Hunninghake GM, 김홍표, Avila L, Barnes KC, Baurley JW, Beaty TH, Bossley CJ, Choi AMK, Gauderman WJ, Gilliland F, Himes BE, Israel E, Klanderman BJ, Lasky-Su J, Liang C, Mathias RA, O'Connor GT, Raby BA, Rafaels N, Ruczinski I, Sharma SS, Soto-Quir?s ME, Sylvia JS, Vora H, Weiss ST, Wilk JB, Bush A, Celed?n JC, TSLP polymorphisms are associated with asthma in a sex-specific fashion., ALLERGY, Vol.65, No.12, pp. 1566-1575 (12월, 2010)
  • [논문] Chen ZH, 김홍표, Emeka Ifedigbo, Harikrishnan Parameswaran, Jiaofei Cao, Jin Y, Lam HC, Ryter SW, Seon-Jin Lee, Choi AMK, Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema., PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol.107, No.44, pp. 18880-18885 (11월, 2010)
  • [논문] 장선영, 고현정, 유희민, 이필준, 조남기, 김홍표, Resource conservation using whole body autophagy: Self-digestion of shedded gut lining cells in the small intestine, 한국식품과학회지, Vol.52, No.3, pp. 244-248 (6월, 2020)
  • [논문] 김홍표, 김영중, Revisiting Hepatoprotective Natural Products from a Biological Point of View, NATURAL PRODUCT SCIENCES, Vol.17, No.3, pp. 165-174 (9월, 2011)
  • [학술회의] Y.Joe, 김홍표, H.Chung, M.Zheng, Uddin, 박정우, A functional link between heme oxgyenase-1 and tristetraprolin in the anti-inflammatory effects of nicotine, 8th International Conference on Heme oxygenases, bioiron and oxidative stress, pp. 65-65 (10월, 2014)
  • [학술회의] 김홍표, 우승제, 이필준, 최광은, Accumulation of heme and lipid mobilization during early hibernation periods, 8th international conference on Heme oxygenases, bioiron and oxidative stress, pp. 68-68 (10월, 2014)
  • [학술회의] 조연수, 정헌택, 김홍표, 김현정, 박정우, 우딘, 장밍, 첸, Tristetraproline mediates anti-inflammatory effect of carbon monoxide against DDS-induced colitis, 8th international conference on Heme oxygenases, bioiron and oxidative stress, pp. 64-64 (10월, 2014)
  • [학술회의] 이필준, 김홍표, 우승제, curcuminoids induce apoptosis of hepatic stellate cells via differential expression and protein interaction of cannabinoid 2 receptor, 한국생약학회 제 43회 정기총회 및 학술대회, (12월, 2012)
  • [저서] 김홍표, 태양을 먹다 - 생명의 고리를 잇는 광합성 서사시, (4월, 2023)
  • [저서] 김홍표, 탄소 교향곡 - 탄소와 거의 모든 것의 진화, (6월, 2022)
  • [저서] 김홍표, Smellosophy, (11월, 2020)
  • [저서] 김홍표, 작고 거대한 것들의 과학, (8월, 2020)
  • [저서] 김홍표, Drunken Monkey (술취한 원숭이), (3월, 2019)
  • [저서] 김홍표, How Science Works(과학원리), (12월, 2018)
  • [저서] 김홍표, 가장 먼저 증명한 것들의 과학, (9월, 2018)
  • [저서] 김홍표, 물의 과학, (8월, 2018)
  • [저서] 김홍표, 숫자로 풀어가는 생물학 이야기, (1월, 2018)
  • [저서] 김홍표, 김홍표의 크리스퍼 혁명, (11월, 2017)
  • [저서] 김홍표, 박정우, 배현옥, 백승훈, 신재균, 정수월, 정헌택, 조연수, 최혜선, Heme Biology, (8월, 2017)
  • [저서] 김홍표, Cells, Gels and the Engines of Life, (1월, 2017)
  • [저서] 김홍표, 먹고 사는 것의 생물학, (12월, 2016)
  • [저서] 김홍표, From Fish to Philosopher, (3월, 2016)
  • [저서] 김홍표, 우리는 어떻게 태어나는가, (8월, 2015)
  • [저서] 김홍표, 진화와 의학, (4월, 2015)
  • [저서] 김홍표, Novum Organum, (7월, 2014)
  • [저서] 김홍표, The Expression of the Emotions in Man and Animal, (5월, 2014)
  • [저서] 김홍표, 제2의 뇌, (11월, 2013)
  • [저서] 김홍표, 산소와 그 경쟁자들, (9월, 2013)
  • [저서] 김홍표, 권용수, 송경식, 안미정, 오좌섭, 윤기동, 이정규, 장대식, 장영표, 정길생, 생약학요약집, (10월, 2012)
  • [저서] 김홍표, 권용수, 송경식, 안미정, 오좌섭, 윤기동, 이정규, 장대식, 장영표, 정길생, 생약학 실습서, (9월, 2012)

특허 및 기타

  • [특허] 김홍표, 김형수, 신일진, 이필준, 레스베라트톨 유도체를 유효성분으로 포함하는 간경화 또는 간섬유화 예방 또는 치료용 약학 조성물, 특허, (등록) (10-1632839) (6월, 2016)