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윤태종Yoon, Tae-Jong

  • 소속 약학과
  • 연구실약학관 310
  • 이메일 tjyoon@ajou.ac.kr / yoontj1@daum.net
  • 내선번호3458

관심분야

  • Nanomaterials, Bio-imaging and sensing, Drug/gene/protein delivery, Theranosis

학력

  • 2006.02 서울대학교 박사

경력

    -. CMIR, MGH, Harvard Medical School, MA, USA (2007 ~ 2009): 
Postdoctoral Research Fellow (Ralph Weissleder)
-. Dept. Applied Bio-Science, College of Biomedical engineering, CHA Univ. (2009 ~ 2015): 
Assistant/Associate  Professor

연구분야

    	? Development of high efficiency magnetic nanoparticle
	? Ultra-sensitive detection by antibody conjugated nanoparticle
	? Cancer targeting and imaging with fluorescent magnetic nanoparticle
	? Application to cell separation and cancer cell therapy using of external magnetic field 
	? Nanoparticle surface modification with various organic molecules 
	? Polymer-nanoparticle organic-inorganic nanohybrid system for various bio-imaging
	? Biocompatible nanomaterial application as a gene or drug delivery carrier 
	? Therapeutics and Diagnosis combination study (Theranosis)
	? Cell function controlling by CRISPR/Cas9 encapsulated nanomaterials
	? NIR dye nanoparticles for the bioimaging guided therapy

대표논문

  • [논문] YI Yoon, YS Kwon, GJ Ahn, H Lee, HJ Jae, HJ Lee, KS Park, SG Park, SH Cho, SH Heo, SH Lee, SI Hwang, YI Kim, YS Cho, 윤태종, Ultrasound-mediated gene and drug delivery using a microbuble-liposome particle system, THERANOSTICS, Vol.4, No.11, pp. 1133-1144 (9월, 2014)
  • [논문] 윤태종, H Lee, H Shao, SA Hilderbrand, R Weissleder, Multicore assemblies potentiate magnetic properties of biomagnetic nanoparticles, ADVANCED MATERIALS, Vol.23, No.41, pp. 4793-4797 (11월, 2011)
  • [논문] 윤태종, H Lee, H Shao, R Weissleder, Highly magnetic core-shell nanoparticles with a unique magnetization mechanism, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Vol.50, No.20, pp. 4663-4666 (5월, 2011)
  • [논문] 윤태종, H Lee, FW Swirski, J Figueiredo, R Weissleder, Rapid detection and profiling of cancer cells in fine needle aspirates, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol.106, No.30, pp. 12459-12464 (7월, 2009)
  • [논문] 윤태종, H Lee, R Weissleder, Ultrasensitive Detection of Bacteria Using Core?Shell Nanoparticles and an NMR-Filter System, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Vol.48, No.31, pp. 5657-5660 (7월, 2009)

연구활동

  • [논문] 김미영, 김민영, 김상섭, 김용준, 김준, 김형수, 백승훈, 윤태종, Feasibility study on the homogeneity and stability of megastigmatrienone isomers for the development of certified reference material, JOURNAL OF FOOD COMPOSITION AND ANALYSIS, pp. 105573-105580 (7월, 2023)
  • [논문] 원은정, 윤태종, 박혜지, 조영석, Gene Therapy Using Nanocarriers for Pancreatic Ductal Adenocarcinoma: Applications and Challenges in Cancer Therapeutics, PHARMACEUTICS, Vol.1, pp. 137-159 (1월, 2022)
  • [논문] 원은정, 권호정, 김진현, 박혜지, 장승희, 윤태종, 조영석, One-shot dual gene editing for drug-resistant pancreatic cancer therapy, BIOMATERIALS, pp. 121252-121261 (11월, 2021)
  • [논문] 류지연, 원은정, Emmanuel Hui, 김호식, 최유정, 윤태종, 조영석, Gene editing particle system as a therapeutic approach for drug-resistant colorectal cancer, NANO RESEARCH, pp. 1-10 (4월, 2020)
  • [논문] 류지연, 김진현, 원은정, 이한아름, 휴이엠마뉴엘, 김홍표, 윤태종, Ultrasound-activated particles as CRISPR/Cas9 delivery system for androgenic alopecia therapy, BIOMATERIALS, pp. 1-11 (12월, 2019)
  • [논문] 류지연, 조은이, 박상규, 이한아름, 홍신희, 박혜선, 홍관수, 김홍표, 윤태종, Lechitin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes, Journal of Nanobiotechnology, pp. 19-31 (1월, 2019)
  • [논문] 조희상, Emmanuel Hui, Kwan Soo Hong, Moon-Sun Jang, Young Il Yoon, shin-woo Ha, 윤태종, Jung Hee Lee, Ions doped melanin nanoparticles as a multiple imaging agent, Journal of Nanobiotechnology, pp. 73-82 (10월, 2017)
  • [논문] 조희상, Dawoon Han, Dong-Hoon Lee, Rohit Chand, Yong-Sang Kim, 윤태종, Highly selective organic transistor biosensor with inkjet printed graphene oxide support system, JOURNAL OF MATERIALS CHEMISTRY B, Vol.5, No.19, pp. 3580-3585 (5월, 2017)
  • [논문] 윤태종, Phuong Ha-Lien Tran, Thao Truong-Dinh Tran, 이범진, Fattigation-platform theranostic nanoparticles for cancer therapy, MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, pp. 1161-1167 (3월, 2017)
  • [논문] K Sim, T Seo, YS Kwon, JK Lee, 윤태종, Y Kwon, Optimization of magnetic hyperthermia effect for breast cancer stem cell therapy, RSC ADVANCES, pp. 107298-107304 (11월, 2016)
  • [논문] 윤태종, 김지혜, 아라이, 안효선, 이수홍, 진수언, 황성주, 성종혁, Boiling Method-Based Zinc Oxide Nanorods for Enhancement of Adipose-Derived Stem Cell Proliferation , TISSUE ENGINEERING PART C-METHODS, Vol.9, pp. 847-855 (8월, 2016)
  • [논문] 윤태종, Byung-Heon Lee, Ga-Hyun Leeq, Hyoungwon Moon, See-Hyong Park, Young Il Yoon, Hak Jong Lee, Development of a novel microbubble-liposome complex conjugated with peptide ligands targeting IL4R on brain tumor cells, ONCOLOGY REPORTS, pp. 131-136 (5월, 2016)
  • [논문] 조희상, 권용수, 신현수, 윤영일, 이학종, 장수진, 조영석, 윤태종, Magnetic Liposomal Particles for Magnetic Imaging, Sensing, and the pH-Sensitive Delivery of Therapeutics, PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, pp. 242-247 (4월, 2016)
  • [논문] HS Jung, JS Cho, YJ Kim, 윤태종, JK Lee, Silica-coated gradient alloy quantum dots with high luminescence for converter materials in white light-emitting diodes, RSC ADVANCES, pp. 107585-107590 (12월, 2015)
  • [논문] KN Yu, 윤태종, J Kim, J Lim, JK Lee, S Chang, SJ Park, M Cho, Titanium Dioxide nanoparticles induce endoplasmic reticulum stress-mediated autophagic cell death via mitochondria-associated endoplasmic reticulum membrane disruption in normal lung cells, PLoS ONE, Vol.10, No.6, pp. e0131208(1)-e0131218(17) (6월, 2015)
  • [논문] KY Ju, YI Yoon, GJ Ahn, HS Cho, JJ Lee, KN Yu, MH Cho, SH Lee, 윤태종, HJ Lee, JK Lee, Enhancement of cancer specific delivery using ultrasound active bio-originated particles, CHEMICAL COMMUNICATIONS, Vol.51, No.46, pp. 9455-9458 (4월, 2015)
  • [논문] YI Yoon, YS Kwon, GJ Ahn, H Lee, HJ Jae, HJ Lee, KS Park, SG Park, SH Cho, SH Heo, SH Lee, SI Hwang, YI Kim, YS Cho, 윤태종, Ultrasound-mediated gene and drug delivery using a microbuble-liposome particle system, THERANOSTICS, Vol.4, No.11, pp. 1133-1144 (9월, 2014)
  • [논문] KS Kim, YI Yoon, HJ Lee, HS Cho, YS Kwon, 윤태종, CH Yoon, Synthesis of gold nanoparticles by electro-reduction method and their application as an electro-hyperthermia system, BULLETIN OF THE KOREAN CHEMICAL SOCIETY, Vol.35, No.6, pp. 1806-1808 (3월, 2014)
  • [논문] 윤태종, Young-Seok Cho, Recent advances in photoacoustic endoscopy, World Journal of Gastrointestianl Endoscopy, Vol.5, No.11, pp. 534-539 (11월, 2013)
  • [논문] 윤태종, AA Ghazani, CM Castro, D Issadore, H Shao, J Chung, R Weissleder, H Lee, Miniatured nuclear magnetic resonance platform for detection and profiling of circulating tumor cells, LAB ON A CHIP, Vol.14, No.1, pp. 14-23 (7월, 2013)
  • [논문] 윤태종, H Lee, H Shao, Ralph Weissleder, Oxidation kinetics and magnetic properties of elemental iron nanoparticles, PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, Vol.30, No.8, pp. 667-671 (6월, 2013)
  • [논문] 윤태종, JM Lee, YS Cho`, Recent developments in nanoparticle-based siRNA delivery for cancer therapy, BIOMED RESEARCH INTERNATIONAL, pp. 1-10 (5월, 2013)
  • [논문] 윤태종, A. Minai, J Kim, JK Lee, KN Yu, MS Jeong, S Ha, SJ Park, SJ kim, MH Cho, Zinc oxide nanoparticle induced autophagic cell death and mitochondrial damage via reactive oxygen species generation, TOXICOLOGY IN VITRO, Vol.27, No.4, pp. 1187-1195 (2월, 2013)
  • [논문] J Cha, JK Lee, Y Kwon, 윤태종, Relaxivity control of magnetic nanoclusters for eifficient magnetic relaxation switching assay, CHEMICAL COMMUNICATIONS, Vol.49, No.5, pp. 457-459 (1월, 2013)
  • [논문] C Min, 윤태종, H Shao, M Liong, R Weissleder, H Lee, Mechanism of magnetic relaxation switching sensing, ACS NANO, Vol.6, No.8, pp. 6821-6828 (7월, 2012)
  • [논문] 윤태종, C Min, D Issadore, H Shao, M Liong, R Weissleder, H Lee, Magnetic nanoparticles and microNMR for diagnostic applications, THERANOSTICS, Vol.2, No.1, pp. 55-65 (1월, 2012)
  • [논문] J Kim, 윤태종, A Minai-Tehrani, C Cho, D Yu, H Jiang, H Kim, H Lee, J Shin, KN Yu, S Chang, S Hong, Y Bang, Y Kim, MH Cho, Suppression of tumor growth in H-ras12V liver cancer mice by delivery of programmed cell death protein 4 using galactosylated poly(ethylene glycol)-chitosan-graft-spermine, BIOMATERIALS, Vol.33, No.6, pp. 1894-1902 (12월, 2011)
  • [논문] 윤태종, H Lee, H Shao, SA Hilderbrand, R Weissleder, Multicore assemblies potentiate magnetic properties of biomagnetic nanoparticles, ADVANCED MATERIALS, Vol.23, No.41, pp. 4793-4797 (11월, 2011)
  • [논문] 윤태종, H Lee, H Shao, R Weissleder, Highly magnetic core-shell nanoparticles with a unique magnetization mechanism, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Vol.50, No.20, pp. 4663-4666 (5월, 2011)
  • [논문] N Sun, 윤태종, D Ham, H Lee, R Weissleder, W Andress, Palm NMR and 1-chip NMR, IEEE JOURNAL OF SOLID-STATE CIRCUITS, Vol.46, No.1, pp. 342-352 (1월, 2011)
  • [논문] KN Yu, 윤태종, A Minai-Tehrani, B Kang, C Chae, D Kim, GR Back, HL Jiang, JE Kim, JH Kim, JT Kwon, JY Shin, KH Lee, MH Cho, SH Chang, SH Hong, SJ Park, SK Hwang, Aerosol Delivery of Small Hairpin Osteopontin Blocks Pulmonary Metastasis of Breast Cancer in Mice, PLoS ONE, Vol.5, No.12, pp. e15623(1)-e15623(9) (12월, 2010)
  • [논문] H Shao, 윤태종, M Liong, R Weissleder, H Lee, Magnetic nanoparticles for biomedical NMR-based diagnostics, BEILSTEIN JOURNAL OF NANOTECHNOLOGY, Vol.1, pp. 142-154 (12월, 2010)
  • [논문] K Kim, 윤태종, A Doi, A Takeuchi, A Yabuuchi, AP Feinberg, B Wen, H Hongguang, H Ji, IL Weissman, J Hanna, J Kim, J Seita, K Ng, KC Cunniff, L Ehrlich, MJ Aryee, N Jung, O Naveiras, P Cahan, P Murakami, R Jaenisch, R Weissleder, RA Irizarry, S Mckinney-Freeman, SH Orkin, GQ Daley, Epigenetic memory in induced pluripotent stem cells, NATURE, Vol.467, pp. 285-292 (9월, 2010)
  • [논문] 윤태종, ES Jang, YS Cho, C Park, G Yi, KS Hong, OR Kim, Y Kim, YS Lee, K Chang, Cetuximab-conjugated magneto-fluorescent silica nanoparticles for in vivo colon cancer targeting and imaging, CANCER LETTERS, Vol.299, No.1, pp. 63-71 (9월, 2010)
  • [논문] JB Haun, 윤태종, H Lee, R Weissleder, Magnetic Nanoparticle Biosensors, WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, Vol.2, No.3, pp. 291-304 (5월, 2010)
  • [논문] JT Kwon, 윤태종, A Minai-Tehrani, B Yoon, DS Kim, H Jin, H Yoon, JInK Lee, K Han, M Choi, S Hwang, Y Kang, MH Cho, Body Distribution of Inhaled Fluorescent Magnetic Nanoparticles in the Mice, JOURNAL OF OCCUPATIONAL HEALTH, Vol.50, No.1, pp. 1-6 (9월, 2009)
  • [논문] 윤태종, C Cheong, C Lee, C Park, E Ahn, HE Park, HY Moon, K Chang, K Lee, KB Seung, SH Ihm, KS Hong, Magnetic resonance tracking of multifunctional nanoparticle-labeled mouse mesenchymal stem cells in a mouse model of myocardial infarction, CURRENT APPLIED PHYSICS, Vol.9, No.1, pp. S12-S14 (8월, 2009)
  • [논문] 윤태종, H Lee, FW Swirski, J Figueiredo, R Weissleder, Rapid detection and profiling of cancer cells in fine needle aspirates, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol.106, No.30, pp. 12459-12464 (7월, 2009)
  • [논문] 윤태종, H Lee, R Weissleder, Ultrasensitive Detection of Bacteria Using Core?Shell Nanoparticles and an NMR-Filter System, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Vol.48, No.31, pp. 5657-5660 (7월, 2009)
  • [논문] 윤태종, A Chundnovsky, H lee, K Croce, M Etzrodt, M Nahrendorf, M Wildgruber, MJ Pittet, P Libby, R Weissleder, FW Swirski, Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors, PLoS ONE, Vol.4, No.5, pp. e5663(1)-e5663(9) (5월, 2009)
  • [논문] 윤태종, C Cheong, C Lee, C Park, E Ahn, HE Park, HY Moon, K Chang, K Lee, KB Seung, OR Kim, SH Ihm, SY Lee, KS Hong, Magnetic resonance imaging of macrophage activity in atherosclerotic plaques of apolipoprotein E-deficient mice by using polyethylene glycolated magnetic fluorescent silica-coated nanoparticles, CURRENT APPLIED PHYSICS, pp. S15-S18 (9월, 2008)
  • [논문] 윤태종, B Ahn, B Lee, C Lee, D Kang, H Johng, H Shin, JInK Lee, JS Yoo, KS Soh, In vivo Fluorescence Imaging of Threadlike Tissues (Bonghan Ducts) Inside Lymphatic Vessels with Nanoparticles, CURRENT APPLIED PHYSICS, Vol.7, No.4, pp. 342-348 (11월, 2006)
  • [논문] 윤태종, B Lee, CH Lee, H Johng, H Shin, JK Lee, JS Yoo, KS Soh, Use of Magnetic Nanoparticles to Visualize Threadlike Structures Inside Lymphatic Vessels of Rats, EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, Vol.4, pp. 77-82 (8월, 2006)
  • [논문] 윤태종, BG Kim, BH Sohn, E Kim, JS Kim, KN Yu, MH Cho, SB Park, SH Yun, JInK Lee, Specific targeting, cell sorting, and bioimaging with smart magnetic silica core?shell nanomaterials, SMALL, Vol.2, No.2, pp. 209-215 (11월, 2005)
  • [논문] 윤태종, BG KIM, HW Kim, JS Kim, JinK Lee, KH Lee, KN Yu, MH Cho, SB Park, SJ Park, Toxicity and tissue distribution of magnetic nanoparticles in mice, TOXICOLOGICAL SCIENCES, Vol.89, No.1, pp. 338-347 (10월, 2005)
  • [논문] 윤태종, BG Kim, BH Sohn, JS Kim, K Lee, KN Yu, M Woo, MS Noh, SB Park, JinK Lee, MH Cho, Cellular Uptake of Magnetic Nanoparticle is Mediated Through Energy-dependent Endocytosis in A549 Cells, JOURNAL OF VETERINARY SCIENCE, Vol.7, No.4, pp. 321-326 (10월, 2005)
  • [논문] 윤태종, BG Kim, JS Kim, KN Yu, JinK Lee, MH Cho, Multifunctional nanoparticles possessing a “magnetic motor effect” for drug or gene delivery, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Vol.44, No.7, pp. 1068-1071 (2월, 2005)
  • [논문] 윤태종, JinK Lee, Woo Lee, YS Oh, Magnetic nanoparticles as a catalyst vehicle for simple and easy recycling , NEW JOURNAL OF CHEMISTRY, Vol.27, No.2, pp. 227-229 (1월, 2003)
  • [논문] 윤태종, jae il kim, JInK Lee, Rh-based olefin hydroformylation catalysts and the change of their catalytic activity depending on the size of immobilizing supporters, INORGANICA CHIMICA ACTA, Vol.345, pp. 228-234 (9월, 2002)
  • [논문] JinK Lee, 윤태종, GS Park, W Lee, JH Choy, A Novel quantum-dot pillared layered transition metal sulfide: CdS-MoS2 semiconductor-metal nanohybrid, JOURNAL OF MATERIALS CHEMISTRY, Vol.12, No.3, pp. 614-618 (1월, 2002)
  • [논문] JinK Lee, 윤태종, YK Chung, Novel smart ligand for immobilizing a highly efficient Rh-catalyst, CHEMICAL COMMUNICATIONS, No.13, pp. 1164-1165 (6월, 2001)
  • [논문] 윤태종, Young Il Yoon, Hak Jong Lee, Optimization of ultrasound parameters for microbubble-nanoliposome complex-mediated delivery, ULTRASONOGRAPHY (USG), Vol.34, No.4, pp. 297-303 (4월, 2015)
  • [논문] MJ Jang, 윤태종, BL Yun, HJ Lee, SI Hwang, YI Yoon, YS Kwon, SN Kim, Trastuzumab-Conjugated Liposome-Coated Fluorescent Magnetic Nanoparticles to Target Breast Cancer, Korean Journal of Radiology, Vol.15, No.4, pp. 411-422 (8월, 2014)
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특허 및 기타

  • [특허] 윤태종, 금속이온이 포함된 멜라닌 나노입자를 유효성분으로 함유하는 다중 영상 조영제용 조성물, 특허, (등록) (10-1942196) (1월, 2019)